The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory
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چکیده
منابع مشابه
The tissue organization field theory of cancer: a testable replacement for the somatic mutation theory.
The somatic mutation theory (SMT) of cancer has been and remains the prevalent theory attempting to explain how neoplasms arise and progress. This theory proposes that cancer is a clonal, cell-based disease, and implicitly assumes that quiescence is the default state of cells in multicellular organisms. The SMT has not been rigorously tested, and several lines of evidence raise questions that a...
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ژورنال
عنوان ژورنال: BioEssays
سال: 2011
ISSN: 0265-9247
DOI: 10.1002/bies.201100025